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Study OA-1 : Two hundred fifty-six patients N128 on Cymbalta, N128 on placebo enrolled and 204 80% completed the study. Patients had a mean baseline pain rating of 6 on a numerical rating scale ranging from 0 no pain to 10 worst possible pain. After 13 weeks of treatment, patients taking Cymbalta had significantly greater pain reduction. Subgroup analyses did not indicate that there were differences in treatment outcomes as a function of NSAIDs use. Arnold LM, Meyers AL, Sunderajan P, Montano CB, Kass E, Trivedi M, Wohlreich MM.
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